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Celebrex is a non-steroidal anti-inflammatory drug (NSAID) of the coxib family (selective inhibitor of cyclooxygenase-2). Mostly used for the symptomatic treatment of rheumatic diseases (osteoarthritis, rheumatoid arthritis and ankylosing spondylitis).

Active ingredient: Celecoxib.
Brands: Celebrex, Celib, Coxib, Cobix, Caditar and many other.

Main effects.

Like other coxib, Celebrex has an anti-inflammatory and analgesic(against pain).

Inhibitors of cyclooxygenase seem to have a preventive effect on the occurrence of colon adenomas, but can become secondarily to cancer. Celebrex has demonstrated efficacy in this use. This does not proven, however, it can reduce the incidence of colon cancer.

Uses

It’s used to treat acute pain, arthritis, and menstrual pain and distress. The pain and relief offered by this medicine can help you execute more of your normal tasks.

If you’re treating a chronic condition like arthritis, ask your physician about remedies and/or using different drugs to treat your pain.

This medication works by blocking the enzyme in your body which makes prostaglandins. Decreasing prostaglandins helps to decrease swelling and pain.

The best way to use Celebrex

Read the Medication Guide provided by your pharmacist before you begin using celecoxib and every time you get a refill. Ask your health care provider or pharmacist in case you have any queries.

Take this medicine as directed by your doctor, usually once or twice . This drug is best taken with meals to lower the chance of stomach upset. Take this medicine at the lowest effective dose and just for the prescribed period of period (see also Warning section).

Take this medicine with a complete glass of water (8 oz or 240 milliliters) unless your doctor directs you otherwise. Don’t lie down for 10 minutes after taking this medicine.

For specific conditions (for example, arthritis), it could take around 2 months of taking this medication regularly before you have the entire benefit.

If you are taking this medication on an “as required” basis (not on a regular schedule), do not forget that pain medications work best if they’re used as the first signs of pain occur. The medicine may not work, should you wait until the pain has worsened.

Since Celebrex is used if needed, you might not be on a program. If you’re following a program, use the missed dose when you remember. Don’t use additional medicine to make up the dose.

Your chance of stomach bleeding might raise.

Avoid even though you are taking Celebrex taking aspirin or other NSAIDs.

Ask a physician or pharmacist before using any cough, cold, or pain medicine. Many medications available over the counter contain aspirin or other medicines. Taking products can cause you to get a lot of the kind of medication. Check the label.

Celebrex: the dosage

Because of the possible increase in cardiovascular risks of Celebrex based on the dose and duration of treatment, this drug should be prescribed at the lowest effective daily dose for the shortest period possible. The need for symptomatic relief and response to therapy the patient should be reevaluated periodically, especially in patients with osteoarthritis (see sections Contraindications, warnings and precautions, side effects and Pharmacodynamic properties).

Osteoarthritis

The usual recommended daily dose is Celebrex 200 mg divided into one or two doses. In some patients with insufficient relief from symptoms, increasing the dose to 200 mg twice daily may increase efficacy. In the absence of improvement in therapeutic benefit after two weeks, other therapeutic options should be considered.

Rheumatoid arthritis

The recommended daily dose is Celebrex 200 mg divided into 2 doses. Buy Celebrex 100 mg

If necessary, the dose may be increased later to 200 mg twice a day. In the absence of improvement in therapeutic benefit after two weeks, other therapeutic options should be considered.

Ankylosing Spondylitis

The recommended daily dose is 200 mg divided into one or two doses. For a small number of patients with insufficient relief from symptoms, increasing the dose to 400 mg divided into one or two doses may increase efficacy. In the absence of improvement in therapeutic benefit after two weeks, other therapeutic options should be considered.

The maximum recommended daily dose for all indications is 400 mg.

Celebrex can be taken with or without food.

Elderly (> 65)

As with any patient, treatment should be started at 200 mg per day.

If necessary, the dose may be increased later to 200 mg twice a day. Particular attention should be paid to elderly body weight below 50 kg (see section Special warnings and precautions and Pharmacokinetic properties).

Liver failure

In patients with moderate hepatic impairment demonstrated with a serum albumin of 25 and 35 g / l, treatment should be initiated at half the recommended dose. Experience in these patients is limited to that of patients with cirrhosis (see sections Contraindications, warnings and precautions for use and Pharmacokinetic properties).

Renal failure

Experience with Celebrex in patients with mild to moderate is limited, such patients should be treated with caution (see sections Contraindications, warnings and precautions for use and Pharmacokinetic properties).

Children

Celebrex is not indicated in children.

CYP2C9 poor metabolisers

The risk of dose-related adverse effects is higher, should be administered with caution to patients Celebrex known or suspected to be CYP2C9 poor metabolizers based on genotyping or history / previous experience with other substrates CYP2C9. A dose reduction to half the lowest dose recommended should be considered.

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